Facial fillers and injectables are substances used to fill out fine lines and wrinkles in the face, restoring a more youthful appearance*. They work by adding volume under the skin around the eyes, cheeks, nasolabial folds, and lips. Botox® (botulinum toxin) works by relaxing or paralyzing certain facial muscles by blocking the nerves that cause the muscle to contract, thus removing the wrinkle. The results for Botox® may last three to four months*, while other fillers and injectables may last up to two years.*.